泰安市主要恶性肿瘤病例对照研究

Taian city case-control study of malignant tumors

目的探讨泰安市主要恶性肿瘤相关危险因素及保护因素。方法对泰安市主要恶性肿瘤食管癌、肺癌、胃癌、肝癌进行1：1配对病例对照研究，应用条件Logistic回归对相关因素进行单因素和多因素分析。结果食管癌和胃癌的共同危险因素为喜食干、硬、烫、油炸、动物性食物，大量饮酒、家族癌症史，主食煎饼与食管癌发病有关；经常吸烟、居住地及其周围有污染源增加肺癌的患病概率；乙肝病毒感染、慢性肝病史、情绪不稳定、暴饮暴食是影响肝癌发病的重要危险因素。经常饮茶对4种恶性肿瘤具有保护作用，生吃大蒜、常吃蔬菜水果、奶类豆类食品对预防食管癌、胃癌的发生均有保护作用。结论在人群中倡导适当锻炼，戒烟限酒，心理平衡，养成良好的饮食和膳食习惯，能够有效预防主要恶性肿瘤的发生。

Objective To investigate the main risk factors and protective factors of malignant tumors in Taian City. Methods Esophagus, lung, stomach, liver Malignancies in Taian City, 1：1 matched casecontrol study, application conditions of the relevant factors, logistic regression univariate and multivariate analysis were done. Results For esophageal and gastric cancer, the common risk factors were eating hot, dry, hard, deep fried foods, and also animal food, heavy drinking, family history of cancer, the staple food pancake with esophageal cancer-related. For lung cancer, heavy smokers, living in and around the sources of pollution, may increase the probability of illness, hepatitis B virus infection, chronic liver disease history, unstable emotion, eating and drinking are the major risk factors for liver cancer. Tea on the four kinds of malignant tumors often have a protective effect. Raw garlic, fruits and vegetables, dairy soy foods can prevent esophageal cancer and gastric cancer. Conclusion To promote proper exercise, stop and smoking alcohol drinking, psychological balance, good dietary habits, can effectively prevent the occurrence of malignant tumors.