慢性肾脏病钙磷代谢紊乱及骨病的处理

Treatment of calcium,phosphate metabolism disorder and renal osteodystrophy in patients with chronic kidney diseases

慢性肾脏病矿物质及骨代谢紊乱是慢性肾脏病患者最常见的慢性并发症之一,长期的骨及钙磷代谢异常不仅会引起骨痛、骨骼畸形,还会导致血管及心瓣膜钙化,心血管事件高发。治疗的重点是降低高血磷和维持血钙,控制甲状旁腺激素在目标范围。

Mineral and bone disorder is one of the most common chronic complications of chronic kidney disease. The long-term metabolism disorder of bone, calcium and phosphate can cause not only bone disease, but also vascular/cardiac valve calcification and high morbidity of cardiac and/or vascular events. The treatment for these complications is mainly aimed to decrease high blood phosphate, maintain blood calcium and keep PTH within defined levels.