弥漫性颅内血管病变的TCD-DSA对比分析

Detection of the diffuse intracranial disease: transcranial doppler versus digital subtraction angiography

目的经颅多普勒(Transcranial Doppler,TCD)血流速度增快已广泛用于评价颅内大血管狭窄,探讨TCD对弥漫性颅内血管病的诊断价值。方法回顾分析270例缺血性脑血管病患者的经颅多普勒(TCD)与数字减影血管造影(digital subtraction angiography,DSA)检测结果。结果TCD(MFV结合PI值异常)在检测弥漫性颅内血管狭窄的特异度性为92.1%、敏感性为75%、假阳性率为80%、假阴性率为89.74%、总准确度为87.03%。结论TCD可作为弥漫性颅内血管病的预防性筛选方法之一。

Objective To evaluate the diagnostic value of TCD in detecting diffuse intracranial disease against digital subtraction angiography （DSA） as Transcranial Doppler （TCD） being widely applied to evaluate the intracranial large artery stenosis based on focal velocity elevations. Methods We retrospectively analyzed patients＇ s DSA and TCD results who had undergone acute ischemic stroke. Results Transeranial Doppler （ abnormal mean flow velocities and Pulsatility index）detection of focal and diffuse intracranial disease had sensitivity75.0% , specificity 92. 1% , positive predictive value 80.0% , negative predictive value 89. 7% , and overall accuracy 87.0% . Conclusion TCD can be used as one of the prophylactic screening tool for the detection of diffuse intracranial disease.