2型糖尿病患者抑郁状况及对生命质量的影响

Study on the relationship between depression and quality of life of type 2 daibetes mellitus

目的了解T2DM患者抑郁发生状况及对生命质量的影响,为制定糖尿病的健康教育和干预措施提供依据。方法采用病例对照研究方法,以SF-36量表和抑郁自评量表分别对T2DM患者和非糖尿病患者的生命质量和抑郁状况进行评分。结果T2DM伴发抑郁的发生率为32.50%,与对照组比较有统计学意义(χ2=34.61,P<0.01)。病程、血糖控制不良、不运动和患有其他并发症是T2DM伴发抑郁症的危险因素,年龄和家庭收入状况是保护性因素。T2DM患者生命质量的八个维度及总分均低于对照组(P值均小于0.05)。除生理功能外,T2DM伴发抑郁与未伴发抑郁生命质量的其他七个维度和总分有统计学意义(P值均小于0.01)。结论T2DM伴发抑郁的发生率为32.50%。T2DM伴发抑郁的生存质量比未伴发抑郁者差。

Objective To investigate the occurrence rate of depression in the type 2 diabete mellitus （T2DM） and analyze the status quo and risk factors of Quality of Life of T2DM with depression, so as to provide scientific basis for making preventive measures of T2DM. Methods A case-control study was used in scoring of Quality of Life or depression of 200 cases and 229 controls by SF-36 and CES-D. Results the occurrence rate of depression in T2DM was 32. 50%, control 9. 61%, among them case occurrence rate was higher than control significantly. Results From multiple-factor non-conditional logistic regression showed that hazards for T2DM with depression were significantly associated with the following factors：long course, lower income, having no exercise, poor control of blood glucose etc. There were significant different between T2DM with depression and nondepression in scoring of Quality of Life. Conclusion The occurrence rate of depression in T2DM was 32. 50%. The quality of life of T2DM with depression was lower than that of T2DM with non-depression.