代谢综合征尿微量白蛋白与冠心病发病的关系研究

目的探讨代谢综合征的尿微量白蛋白与冠心病发病的关系。方法随机选取147例代谢综合征患者，统计患者的冠心病发病情况，测定其尿微量白蛋白。根据尿微量白蛋白量将研究对象分组，比较两组冠心病发病率，并以冠心病事件为因变量、尿微量白蛋白和年龄为自变量进行Logistic回归分析。结果尿微量白蛋白正常组冠心病发病率显著低于增高组（P=0．042），成功建立了尿微量白蛋白、年龄因素和冠心病事件的Logistic回归模型（P=0．035）。结论尿微量白蛋白可能在预测冠心病发病率有一定价值。

Objective To explore relationships of microalbuminuria（mAlb） and coronary heart disease in patients with metabolic syndrome （MS）. Methods We randomly assigned 147 patients with MS and collected information of coronary heart disease and mAlb from individuals. We performed correlation and regression analysis for them. For coronary heart disease ,we performed means compare analysis and logistic regression analysis. Results We can find that occurrence of coronary heart disease in normal group were significantly less than that of another group （ P = 0. 042 ）. We successfully generated a Logistic regression function with independences of mAlb and age （ P = 0. 035 ）. Conclusion MAlb may predict oecurrence of coronary heart disease in patients with MS.