葛根素治疗急性心肌梗死的疗效观察

Observation of the effect of puerarin used in acute myocardial infarction

目的观察葛根素注射液治疗急性心肌梗死患者的临床疗效及对其血清高敏c反应蛋白（hs-CRP）、白细胞介素-6（IL-6）水平的影响。方法48例急性心肌梗死患者随机分为两组，对照组用常规药物治疗，治疗组在常规治疗的基础上加用葛根素注射液。血清hs-CRP采用免疫比浊法测定，IL-6采用酶联免疫吸附测定法测定。结果治疗组疗效明显优于对照组（P〈0．05）。两组患者血清hs-CRP、IL-6浓度较治疗前均明显降低（P〈0．01），治疗组下降更明显，组间有显著性差异（P〈0．05）。结论葛根素注射液可明显改善急性心肌梗死患者临床疗效，显著降低急性心肌梗死患者血清hs-CRP、IL-6水平，提示葛根素注射液对急性心肌梗死的治疗作用与减轻炎症反应有关。

Objective To observe the clinical curative effect of puerarin Injection used in acute myocardial infarction patients and the effect on the level of hs-CRP and IL-6. Methods 48 acute myocardial infarction patients were randomly divided into two groups, the control group treated with the routine therapy and the treatment group treated with puerarin injection based on the routine therapy. The hs-CRP of blood-serum was measured with ITM and IL-6 was measured with enzyme-linked immunosorbent assay. Results The effect of the treatment group was obviously better than that of the control group（ P 〈 0. 05 ）. The level of hs-CRP and IL-6 of blood-serum were obviously degraded after treatment （ P 〈 0.05 ）. The treatment group was more obviously degraded after treatment than the control group （P 〈 0. 05）. Conclusion Puerarin injection can obviously improve the clinical curative effect on the acute myocardial infarction patients by notable depressing the level of hs-CRP and IL-6.