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多发性骨髓瘤的免疫表型特征的研究进展 被引量:2

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摘要 采用流式细胞术研究多发性骨髓瘤(MM)的免疫表型特征,浆细胞特异标志物有CD38、CD138和CD56,其中CD138对MM患者骨髓浆细胞浸润的评估有临床价值,CD56有望可作为多发性骨髓瘤早期预测病程进展及预后的指标。髓系抗原CD117和CD33的表达可能与MM的预后相关。CD28的表达与MM疾病进展存在相关趋势。采用多参数流式细胞术监测微小残留病灶可考虑作为MM独立的预后因素。
出处 《中国临床实用医学》 2010年第2期249-251,共3页 China Clinical Practical Medicine
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  • 1杜庆华,许艳丽,毛平,王顺清,李庆山.多发性骨髓瘤CD38及CD56表达的研究[J].中国热带医学,2006,6(10):1795-1796. 被引量:3
  • 2黄春妮,李山,秦雪.流式细胞术测定多发性骨髓瘤细胞表面标记的研究[J].广西医学,2007,29(7):953-956. 被引量:9
  • 3PAIVA B, ALMEIDA J, PEREZ-ANDRES M, et al. Utility offlow cytometry immunophenotyping in multiple myeloma and otherclonal plasma cell-related disorders[J]. Cytometry Part B (ClinicalCytometry) 2010, 78(4): 239-252.
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