灵猫香解毒丸的质量标准研究

Study on quality standards for Lingmaoxiang Jiedu pills

目的:制定灵猫香解毒丸的含量测定标准。方法:采用反相高效液相色谱法测定蟾酥中华蟾酥毒基和酯蟾毒配基。结果:华蟾酥毒基和酯蟾毒配基分别在48.84～784.44,50.28～804.48ng与峰面积呈良好线性关系,平均回收率100.5%,100.3%。结论:本实验定量方法简便、实用,重复性好,能够较好控制灵猫香解毒丸的质量。

Objective： To establish the quality standards of Linmaoxiang Jiedu pills. Method： Cinobufagin and bufogenin were determined by HPLC simultaneously. Result： The average recoverys of Cinobufagin and bufogenin was 100. 5% and 100. 3% , their linear range were 48.74-731.10 ng and 49.90-748. 50 ng, respectively. Conclusion： The method for quantification is reproducible and realizable. The method can be used to coutrol quality of Linmaoxiang Jiedu pills as the quality standards.