厚壳树叶化学成分研究

Chemical contituents in leaves of Ehretia thyrsiflora

目的:对厚壳树Ehretia thyrsiflora干燥叶粗提物的各个部位进行化学成分研究。方法:利用硅胶柱色谱,Sepha-dex-LH20,反相C18柱色谱等手段进行分离纯化,根据理化性质和波谱数据进行结构鉴定。结果:从二氯甲烷及正丁醇部位分离了得到6个化合物,分别为β-谷甾醇(β-sitosterol,1),咖啡酸乙酯(ethyl caffeate,2),2-甲氧基苯甲酸辛酯(2-methoxylben-zoic acid octylester,3),十四烯酸甘油酯(tetradecenoic acid,2,3-dihydroxypropyl ester,4),胡萝卜苷(daucoster,5),尿囊素(al-lantoin,6)。结论:化合物1～5为首次从该种植物中分离得到,化合物2～5为首次从该属植物中分离得到。

Objective： To investigate the chemical constituents of Ehretia thyrsiflora. Method： Compounds were isolated with silica gel, Sephadex LH-20 and RP-C18 colum chromatography. Their structures were elucidated by means of physico-chemical properties and spectral analysis. Result： Six compounds were isolated and identified as β-sitosterol （1）, ethyl caffeate （2）, 2-methoxyl benzoic acid octyl ester （ 3 ）, tetradecenoic acid, 2,3-dihydroxypropyl ester （ 4 ）, daucoster （ 5 ）, allantoin （ 6 ）. Conclusion ： Compounds 1-5 were obtained from this st3ecies for the first time. Compounds 2-5 were obtained from the genus Ehretia for the first time.