摘要
目的:观察癫宁片治疗顽固性癫痫的临床疗效。方法:将180例顽固性癫痫患者随机分为治疗组和2个对照组,每组各60例。治疗组给予本院生产的癫宁片,对照组分别给予卡马西平片+氯硝安定片和丙戊酸钠片+氯硝安定片,治疗6个月后比较疗效。结果:癫宁片治疗顽固性癫痫的总有效率、发作次数、脑电图改善情况均优于2个对照组(P<0.05)。结论:癫宁片对顽固性癫痫可取得满意的疗效,且不良反应小。
OBJECTIVE： To approach efficacy of Dianning tablet in the treatment of refractoriness epilepsy. METHODS： 180 patients with refractoriness epilepsy were randomized into treatment group, control group Ⅰ and control group Ⅱ （n=60）. Treatment group were given Dianning tablet produced by our hospital. Control group I were treated with carbamazepine tablet and clonazepam tablet while control group U were treated with valproate sodium tablet and clonazepam tablet. The efficacies of three groups were compared after 6 months. RESULTS： Treatment group was better than control groups in total effective rate, seizure frequency and improvement of EEG （P〈0.05）.CONCLUSION： Dianning tablet shows satisfactory effect on refractoriness epilepsy with little adverse reaction.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第7期645-646,共2页
China Pharmacy
关键词
顽固性癫痫
癫宁片
卡马西平
丙戊酸钠
氯硝安定
Refractoriness epilepsy
Dianning tablet
Carbamazepine
Valproate sodium
Clonazepam
