肝硬化患者联合检测甲状腺激素及甘胆酸的意义

Alterations of serum glycochoilc acid and thyroxine in patients with liver cirrhosis

目的:探讨肝硬化患者甲状腺激素(T_3、T_4)及血清结合胆酸(CG)的诊断意义和相互间的关系.方法:用放免法测定80例肝硬化病人血清中的T_3、T_4及CG并与正常对照组相比.结果:肝硬化与正常对照组比较在CG、T_3、T_4差别有显著性,CG在肝硬化病人明显升高,T_3、T_4在肝硬化病人降低.结论:联合检测甲状腺激素及甘胆酸对肝硬化病人有重要意义.

Aims: To study the diagnostic significance of serum glycocholia acid and thyroxine for liver cirrhosis.Methods: The concentrations of serum glycocholic acid and thyroxine in 80 patients with liver cirrhosis were detected by using RIA. Results: Serum glycocholic acid levels in patients with liver cirrhosis were much higher than those in healthy people,while serum thyroxine was much lower in patients with liver cirrhosis than those in healthy people. Conclusions; The concentrations of serum glycochlic acid and thyroxine are useful in evaluating the severity and prognosis of patients with liver cirrhosis.