高原胸部枪弹伤远隔部位脏器损伤的实验研究

A EXPERIMENTAL STUDY OF DAMAGE OF ORGANS REMOTE FROM TNORAXIC BULLT TRAUMA IN DOGS AT HIGH ALTITUDE

目的：探讨高原缺氧下，犬右胸部枪弹伤后远隔器官损伤的组织学和超微结构改变以及伤情转归的防治措施。方法：各选１５只高原杂种犬分为对照组和预防组，致伤后２４ｈ活杀对照观察。结果：高速投射物致伤后对远隔器官产生较明显的远达效应。对照组病理组织学及超微结构损伤严重，但以器官组织本身的超微结构损伤为主。预防组损伤明显减轻，主要表现为器官组织本身的病理组织学改变。结论：上述改变可能与高速投射物致伤时产生的冲击波、流体动力学改变，以及高原缺氧有关。高原投射物的远达效应，尽管器官改变不很严重。

Objective:To evaluate the changes of histology and ultrastructure of organs remote from thoraxic bullet trauma for preventing their damage at altitude hypoxia(3 658m).Methods:30 morgrel dogs were divided into a control group and a preventive group equivalently and killed to study after 24hr traumatized chest.Results:There was a obvious remote-effects of fire-arm injury in chest on organs remote from this traume.The changes of histology and ultrastructure were severer in control group than in preventing group.Conclusions:The pathological changes of organs remote from trauma could be associated with shocking wave of bullet resulted in trauma of chest,changes of hemadynamics and altitude hypoxia.