液基薄层细胞学联合阴道镜检查应用于250例宫颈病变的诊断价值探讨

目的探讨液基薄层细胞学(TCT)联合阴道镜检查在宫颈病变中的诊断价值。方法对我院门诊就诊的827例患者行TCT检查,对其中250例TCT检查细胞学阳性患者行阴道镜检查和镜下组织活检,对结果进行分析。结果827例患者中正常范围内占69.8%,宫颈炎性病变占19.7%,未明确诊断意义的非典型鳞状上皮细胞(ASC)及非典型腺细胞(AGC)占4.4%,宫颈上皮内病变占3.6%,宫颈癌占2.5%。活检证实在HSIL中CINⅡ9例,CINⅢ7例,宫颈癌21例。其中LSIL吻合率73.7%,HSIL吻合率69.6%,SCC吻合率100%。TCT检查联合阴道镜检查达到较高吻合度。结论TCT筛查可提高宫颈病变阳性诊断率;细胞学阳性患者联合阴道镜检查和镜下组织活检诊断,可发现早期宫颈上皮内瘤变,进一步提高诊断率,为治疗赢取主动,从而提高患者的生存质量。

Objective To explore diagnostic value of thinprep cytology test（TCT） combined colposcopy applied in cervical disease. Methods 827 cases of patients in hospital were checked with TCT, and 250 cases of patients who showed TCT masculine result were checked with Colposcopy and tissue biopsy further, the results were analyzed then. Results The result showed that, the normal was 69.8%, Inflammatory of cervix uteri was 19.7%, ASC and AGC un-clearly diagnosed was 4.4%, CIN was 3.6%, cervical carcinoma was 2.5%. tissue biopsy confirmed that CIN Ⅱ 9 cases, CINⅢ 7 cases in HSIL, and cervical carcinoma was 21 cases. The tally rate of LSIL was 73.7%,and HSIL was 69.6%, SCC was 100%. TCT combined colposcopy reached higher inosculation. Conclusion TCT screening can improve positive diagnosis rate for cervical disease; the check for TCT masculine patients combined colposcopy and tissue biopsy can find cervical intraepithelial neoplasia, improve the diagnosis further, which can win initiative for treatment and improve the life quality of patients.