微量元素锌对婴幼儿反复呼吸道感染疗效观察

Curative Effect Observation on Infants with Recurrent Respiratory Tract Infection Treated by Zinc

目的:观察婴幼儿反复呼吸道感染微量元素锌治疗疗效。方法:选择婴幼儿反复呼吸道感染且血锌值低于正常的门诊患儿60例,随机分成观察组、对照组各30例。观察组在常规治疗基础上补锌治疗,每日剂量为元素锌0.5mg/kg,连服2个月。对照组常规治疗。观察两组治疗后1个月、2个月血锌值变化及治疗结束后1年内呼吸道感染的发病率、药物毒副作用(包括消化道反应及对血铜、血铁及肾功能的影响等)。结果:观察组患儿治疗后1个月、2个月血锌值明显高于对照组,治疗结束1年内,观察组呼吸道感染发病率明显低于对照组,无毒副作用。结论:锌对反复呼吸道感染有一定的疗效,值得推广。

Objective:To observe treatment effect of zinc when using to therapy the infants and young children with recurrent respiratory tract infection.Methods:60 cases of out-patient children and infants with recurrent respiratory tract infection and serum zine values less than the normal were selected and were randomly divided into two groups (30 cases in control group while 30 cases in observe group).Contrast to the control group treated with the conventional therapy only,a daily dose of 0.5mg/kg zinc for 2 months was served to the observe group.The change of the serum zinc values within 1 month and 2 months was observed in both groups,furthermore,the incidencee of respiratory tract infection 1 year after end of treatment and the drug toxicity were observed,too.Results:The value of serum zinc 1 and 2 month after treatment of the observed group was significantly higher than the control group.The incidence of respiratory tract infection 1 year after treatment in the observd group was significantly lower than the control group.Non-toxic side effects were observed.Conclusion:The effect of zinc on recurrent respiratory tract infection have a certain effect,it is worth promoting.