桃红四物汤加味治疗脑外伤后综合征的临床观察

Observation of Taohong Siwu decoction on the treatment of post-traumatic brain syndrome

目的观察桃红四物汤加味治疗脑外伤后综合征的临床疗效。方法选择68例脑外伤后综合征患者,随机分为2组。对照组予茴拉西坦片和草木犀流浸液片口服治疗,治疗组在对照组基础上予桃红四物汤加味口服。观察2组临床症状及脑血流平均峰流速度的变化。结果治疗组治疗组头痛、头昏、记忆力下降、失眠改善情况优于对照组(P<0.05);治疗组总有效率82.4%,对照组总有效率达50.0%,2组总有效率比较差异有统计学意义(P<0.05),治疗组疗效优于对照组;治疗组大脑中动脉(MCA)、基底动脉(BA)脑血流平均峰流速度较对照组降低(P<0.05),治疗组改善优于对照组。结论桃红四物汤加味能够改善脑外伤后综合征临床症状,降低脑血流平均峰流速度,提高临床疗效。

Objective To observe clinical efficacy of Taohong Siwu decoction in treating patients with post - traumatic brain syndrome. Methods 68 patients with post - traumatic brain syndrome were randomly divided into two groups. Patients in the control group were treated with aniraeetam, and melilotus extract tablet. And eases in the treatment group were treated by combination of Taohong Siwu decoction and routine therapy. Changes of clinical syndromes and cerebral blood flows in two groups were observed. Results Improvement of headache, dizzy, remembrance descend and insomnia in the treatment group were superior to those in control group （ P 〈 0.05 ）. The total effective rate in treatment group （ 82.4% ） was higher than that in control group （ 50.0%, P 〈 0.05 ）. And the mean peak blood flow velocities of middle cerebral artery （MCA） and basilar artery（BA） in treatment group were decreased in comparison with those in control group （ P 〈 0.05）. Conclusion Taohong Siwu decoction can ameliorate the clinical syndromes in patients with post - traumatic brain syndrome, and decrease the cerebral blood flow velocities, enhance the therapeutic effect.