B超引导下空芯针肿块穿刺法在乳腺癌诊断中的应用

The value of ultrasound-guided core needle biopsy and frozen section in breast cancer diagnosis

目的探讨B超引导下空芯针穿刺及冰冻检查法对乳腺癌的诊断价值。方法对41例B超怀疑为乳腺癌的患者用Bard活检针在B超引导下进行肿块穿刺，穿刺组织即送冰冻病检。并与同期怀疑乳腺癌但在手术室行开放性切除42例作一临床对比（B组）。结果冰冻切片通常在30～40min有结果。39例为恶性肿瘤，其中浸润性导管癌36例，小叶浸润性癌3例，重度非典型增生2例。每例完成手术时间分别在60—120min，平均（68．19±12．41）min。确诊率为95．1％。B组确诊乳腺癌42例，确诊率为97．6％（P〉0．05），完成一例手术在120～150min，平均时间（127．88±11．50）min（P〈0．01）。结论B超引导下空芯针肿块穿刺法能提高乳腺癌的诊断率、利于制定手术方案及明显缩短手术时间。

Objective To explore the diagnosis value of ultrasound-guided core needle biopsy （CNB） and frozen section in breast cancer. Methods There were 41 cases of breast tumor which were suspicious with ultrasonography, and using Bard automatic biopsy device was applied for percutaneous puncture by ultrasound-guided in breast neoplasms. Tissue samples were harvested for frozen section pathologic examination, compared with 42 clinical eases of the tumour which suspicious with ultrasonography were excised in operation room（ B group） during the same time. Results The outcome of frozen sections were finished in 30 - 40 miutes. Thirty-nine cases were diagnosed to be malignant, 36 eases were infiltrated ductal earcino and 3cases were infiltrated lobular carcinoma , two eases were severely non-type hyperplasia the sensitivity of sonographically guided CNB for the diagnosis of breast cancer was 95.1%. one operation was finished in 60 to 120 minutes, the average is 68.19 ± 12.41 minutes. In group B, sensitivity of diagnosis of breast cancer was 97.6% （ P 〈 0. 05 ）. One operation was finished in 120 to 200 minutes, the average was127. 88 ± 11.50 minutes（ P 〈 0.05）. Conclusion It can achieved highly diagnostic rate, and have benefit of setting down the operations program and the operating time was curtailed when breast cancer was utrasound-guided by CNB and examinede with frozen section.