乙型肝炎病毒标志物表现模式与AFU、ALT、GGT的相关性分析

The analysis of correlation between the performance of HBV markers and AFU, ALT, GGT

目的探讨乙型肝炎病毒（HBV）标志物表现模式与AFU、ALT、GGT的相关性。方法对570例HBV感染者，按不同表现模式分为4组，与150例阴性者对照，用速率法分别检测AFU、ALT和GGT，对各组之间的差异进行评价。结果不同表现模式AFU、ALT、GGT与对照组比较显示：1组、2组和3组的差异有统计学意义（P〈0．01），与第4组的差异无统计学意义（P〉0．01）；各表现模式AFU与ALT、GGT之间的相关性显示：1组、2组和3组的AFU与ALT、GGT之间变化为正相关；而AFU与ALT、GGT之间相关性不明显；不同表现模式血清酶活性升高的分布情况显示：1组、2组和3组的AFU与ALT、GGT均有不同比例的升高。结论HBV标志物与AFV、ALT、GGT有一定的相关性。监测肝细胞的损害程度有助于肝炎病情发展的预测。

Objective To investigate the correlation between hepatitis B virus （HBV） markers and AFU, ALT,GGT. Methods 570 cases of HBV-infected people were divided into 4 groups according to the different performance modes. 150 healthy people were considered as control group, rate method was used to detect AFU,ALT and GGT. Estimate the differences between the groups were compared. Results The comparison between the AFU,ALT, GGT in different performance mode of HBV and the control group showed ： the differences of group 1, group 2 and group 3 were statistically significant （P 〈 0. 01 ）, the difference of group 4 was not significant （P 〉 0. 01 ）. The correlation between AFU,ALT,GGT of different performance mode showed：the changes of AFU and ALT,GGT in group 1, group 2 and group 3 were positively change-related. But the changes of AFU,ALT and GGT were not clearly related. The distribution of the rise of serum enzyme activity in different performance mode showed ： the AFU, ALT and GGT rised in different proportion in group 1 ,group 2 and group 3. Conclusions The AFU,ALT and GGT activity of HBV- infected persons should be detected at the same time, and evaluate the damage of liver cells. This will do help to predict the progression of hepatitis.