昆明地区小儿急性下呼吸道肺炎支原体感染的临床研究

Analysis on Children with Acute Lower Respiratory Infection Caused by Mycoplasma Pneumoniae In Kunming

目的了解肺炎支原体在儿童急性下呼吸道感染中的发生率和临床特征。方法对2006年4月至2007年3月临床诊断为急性下呼吸道感染的1033例住院患儿取静脉血2mL,取血清在生物薄片马赛克TM上用间接免疫荧光法检测病原体的抗体。结果1033例中共检出肺炎支原体71例,检出率为6.87%。单纯肺炎支原体感染52例(5.03%),混合感染19例(1.84%)。各年龄组MP感染率分别为1个月至1岁1.69%、～3岁13.78%、～6岁18.27%、～14岁19.23%。全年均可检出MP,且无季节差异。所有病例用阿奇霉素治疗2～3周均治愈。结论本地区肺炎支原体感染现象普遍。血清学MP-IgM检测是早期诊断的必要手段,阿奇霉素是有效的治疗药物。

Objective To understand the prevalence and clinical features in children with acute lower respiratory infection （ALRI） caused by mycoplasma pneumaniae （MP）. Methods From April 2006 to March 2007, vendor blood of 2 ml were taken from 1033 patients diagnosed as ALRI, the blood serum were checked on the biotic thin slice mosaicTM by indirect immunofluorescence. Results Among 1033 patients, there were 71 MP isolated, the rate was 6.87 % , pure MP 52 cases （5.03 % ） , compound infections 19 cases（ 1.84% ）. The rates of the MP infections in different years were：one month to 1 year1. 69% ,- 3 years 13.78% ,- 6 years 18.27 % ,- 14 years 19.23 %. The rates of the MP infections were no difference in season. All the cases were cured after being treated with azithromycin for 2 to 3 weeks. Conclusion MP infection is more common in children in Kunming. The test of serum MP- IgM should be conducted for early diagnosis. Azithromycio is an effective agent to treat MP.