摘要
目的探讨血清淀粉样蛋白A(SAA)在肾移植术后排斥反应诊断中的价值。方法应用BNproSpec特定蛋白检测仪检测肾移植患者6例及健康者50例血清SAA、C反应蛋白(CRP)的含量。应用日立7600型全自动生化分析仪检测Bu、Cr的含量。结果健康者血清SAA平均值为2.49mg/L。肾移植患者术前血清SAA均值为11.0mg/L,术后第6-10天血清SAA达到峰值。术后发生排斥反应时,SAA水平明显升高且早于Cr水平的升高。结论肾移植术后血清SAA的异常升高较血清Cr更为敏感,可用于肾移植术后急性排斥反应的预测。
Objective To study the value of serum amyloid （SAA） in diagnosis of rejection after kidney transplantation. Methotis The levels of SAA and CRP were determined by BN proSpec in 6 patients after kidney transplantation and 50 healthy people. The levels of Bu and Cr were determined by hatachi-7600 fully automatic biochemical analyzer. Results The average level of SAA in the healthy group was 2.49 mg/L. The average level of SAA in 6 patients before kidney transplantation was 11.0 mg/L. From 6 to 10 days after kidney transplantation, the level of SAA increased to the highest level. The level of SAA increased significantly when acute rejection was happened,and it was more sensitive than Cr. Conclusion The increase of SAA is more sensitive than Cr after kidney transplantation, and it can indicate acute renal rejection after kidney transplantation.
出处
《中国实验诊断学》
北大核心
2010年第2期242-243,共2页
Chinese Journal of Laboratory Diagnosis
