应用序贯器官衰竭评分评价急性有机磷中毒患者的病情及预后

Application of Sequential Organ Failure Assessment(SOFA)on Evaluation of Condition and Prognosis of Patients with Acute Organophosphorus Pesticide Poisoning

目的:探讨序贯器官衰竭评分(SOFA评分)在急性有机磷中毒患者病情及预后评价中的应用价值。方法:将符合条件的135例患者按结局分为死亡组和存活组,进行分段SOFA评分,就其结果进行统计学分析。结果:入院即刻累计、入院48 h累计SOFA评分及两者之差在两组间的差异均存在统计学意义(均P值<0.01);其中心血管和神经系统评分是预后的独立危险因素(均P值<0.05)。结论:SOFA评分结果与急性有机磷中毒患者的病情及预后存在相关性,动态应用可为其提供有价值的参考。

Objective：To investigate the application of sequential organ failure assessment （SOFA） in evaluation of outcome of patients with acute organophosphorus pesticide poisoning（AOPP）. Method.. A retrospective review of 135 standards compliant patients was carried out. SOFA was counted at different time and the result was compared. Results： Between survivors and victims, there were all significant difference in SOFAs counted at admission, SOFAs counted at 48 hours after admission and the difference of them （P〈0.01 totally）. The SOFA of cardiovascular and nervous systems were the independent predictors （P〈0.05 totally）. Conclusions： The result of SOFA is correlative with the prognosis of patients with AOPP. Observing SOFA dynamically can provide a practical method in evaluating the condition and prognosis of patients with AOPP.