垂体大腺瘤临床及MRI特点在不同性别间的比较

Comparison of clinical and MRI characteristics of pituitary macroadenoma between different genders

目的比较男性和女性垂体大腺瘤的临床及MRI特点。方法230例(男104例,女126例)经病理证实的垂体大腺瘤患者按性别分为两组,分别计算每组的平均年龄、瘤体内出血和海绵窦受累的比率、肿瘤体积,并进行组间比较,同时比较两组病例的病理类型构成。结果男性组年龄、瘤内出血率、海绵窦受累率及肿瘤体积分别为(44.8±13.2)岁、21.15%(22/104)、50.00%(52/104)及6100.48mm3;女性组分别为(44.8±11.9)岁、28.57%(36/126)、48.41%(61/126)及5037.05mm3。两组病例的年龄、瘤内出血率、海绵窦受累率、肿瘤体积及病理类型构成无统计学差异(P=0.972,P=0.197,P=0.811,P=0.189,P=0.093)。结论垂体大腺瘤的临床及MRI特点无性别差异。

Objective To compare the clinical and MRI characteristics of pituitary macroadenoma between male and female patients. Methods Two hundred and thirty patients with pathologically diagnosed pituitary macroadenomas （104 mlaes and 126 females） were divided into two groups according to different gender. Patient age, the ratio of intratumoral hemorrhage and cavernous sinus invasion, and tumor volume were calculated in each group and compared between the two groups. The constitution of different pathological types was also compared. Results The age, ratio of intratumoral hemorrhage and cavernous sinus invasion, and tumor volume was （44.8±13.2） years old, 21.15% （22/104）, 50.00% （52/104）, and 6100.48 （mm^3 , median） in the male group and （44.8±11.9） years old, 28.57% （36/126）, 48.41% （61/126） and 5037.05 （mm^3 , median） in the female group, respectiveluy. There was no statistical difference between the two groups regarding to patient age, the ratio of intratumoral hemorrhage and cavernous sinus invasion, tumor volume, and constitution of pathological types （P=0. 972, P=0. 197, P=0. 811, P=0. 189, P=0. 093, respectively）. Conclusion Pituitary macroadenomas show no gender preference in clinical and MRI characteristics.