摘要
目的研究当归[Angelica Sinensis（Oliv.）Diels]的大极性化学成分。方法应用多种色谱方法进行分离纯化,通过1H-NMR、13C-NMR等波谱技术确定化合物的结构。结果分离得到9个化合物,分别鉴定为反式阿魏酸（trans-ferulic acid,1）,顺式阿魏酸（cis-ferulic acid,2）,川芎内酯Ⅰ（senkyunolideⅠ,3）,布雷菌素A（brefeldin A,4）,五加苷B1（eleutheroside B1,5）,E-松柏苷（E-coniferin,6）,愈创木基丙三醇（guaiacylglycerol,7）,淫羊藿次苷F2（icariside F2,8）,马鞭草烯酮-5-O-β-D-葡萄糖苷（verbenone-5-O-β-D-glucopyranoside,9）。结论化合物5~9均为首次从该属植物中分离得到。
OBJECTIVE To investigate the water-soluble constituents of the root of Angelica sinensis （ Oliv. ） Diels. METHODS The chemical constituents were isolated by various chromatography techniques, and structurally elucidated by spectral evidence together with physiochemical analysis. RESULTS Nine compounds were isolated from the water extract of Angelica sinensis, and their structures were identified as trans-ferulic acid （1）, cis-fenllic acid （2）, seukyunolide I （3）, brefeldin A （4）, eleutheroside B1 （5）, E-coniferin （6）, guaiacylglycerol （7）, icariside F2 （8） and verbenone-5-O-β-D-glncopyranosid （9）. CONCLUSION Compounds 5-9 were isolated flom Angelica sinensis for the first time.
出处
《中国药学杂志》
CAS
CSCD
北大核心
2010年第2期101-103,共3页
Chinese Pharmaceutical Journal
基金
上海市科学技术委员会科研项目资助课题(04DZ19851)
关键词
当归
化学成分
Angelica sinensis
chemical constituents
