毛萼紫薇化学成分研究

Chemical Constituents of Lagerstroemia balansae Koehne

目的 研究毛萼紫薇（Lagerstroemia balansae Koehne）的化学成分。方法采用各种色谱技术分离纯化化合物，并通过理化性质和波谱学方法鉴定化合物的结构。结果从毛萼紫薇茎的95％乙醇提取物中分离得到7个化合物，分别鉴定为ficuscarpanoside A（Ⅰ）、反式-阿魏酸二十八烷酯（trans—femlicacidoctacosyl ester，11）、lyoniside（Ⅲ）、gomisin N（Ⅳ）、正一三十烷醇（n—tfiacontanol，Ⅴ）、β-谷甾醇（β-sitosterol，Ⅵ）和胡萝卜苷（daucosterol，Ⅶ）。结论以上化合物均为首次从该植物中获得，其中化合物Ⅰ～Ⅴ为首次从紫薇属植物中分离得到。同时本实验还在2D—NMR的基础上对化合物Ⅰ在DMSO-d6中的1H—NMR和13C—NMR数据以及化合物Ⅰ在DMSO—d6中的1H—NMR数据进行了全归属，并纠正了文献中化合物Ⅲ13C—NMR数据的错误归属。

OBJECTIVE To study the chemical constituents of Lagerstroemia balansae Koehne. METHODS The crude herb of the stems of L. balansae was extracted with 95% EtOH and isolated by repeated chromatographic methods. The structures of the isolated compounds were elucidated by physicochemical and spectral analysis. RESULTS Seven compounds were yielded and identified as： ficuscarpanoside A （ Ⅰ）, trans-ferulic acid octacosyl ester （ Ⅱ ） , lyoniside （ Ⅲ）, gomisin N （ Ⅳ）, n-triacontanol （ Ⅴ）, β-sitosterol （Ⅵ） and daucosterol （ Ⅶ ）. CONCLUSION All compounds were isolated from this plant for the first time, and compound （ Ⅰ - Ⅴ） were obtained from the genus Lagerstroemia for the first time. On the basis of 2D-NMR spectra the 1 H and 13 C-NMR signals of Ⅰ , the 1H-NMR signals of m in DMSO-d6 were assigned totally and the uncorrected assignment of 13C-NMR signals of Ⅲ in the literature were revised.