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P16基因在胃癌中的表达

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摘要 为研究胃癌中P16基因在蛋白水平的表达,应用蛋白A金探针免疫组化技术对30例胃癌和20例正常胃粘膜标本P16进行分析。结果所有正常对照组均有P16表达,其阳性细胞百分数为72.55%±17.22%,而胃癌组为54.90%±28.90%,明显低于正常对照(t=2.100,P<0.05)。胃痛组中23.3%(7/30)P16表达减低,10%(3/30)未表达。提示胃癌中有P16的异常表达,免疫组化技术可较准确地反映P16的表达,更适合于临床研究。
出处 《浙江医学》 CAS 1998年第12期737-738,共2页 Zhejiang Medical Journal
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二级参考文献1

  • 1吕有勇,中华消化杂志,1996年,16卷,9页

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