期刊文献+

细胞凋亡的概念、调节及与幽门螺杆菌感染 被引量:1

下载PDF
导出
摘要 幽门螺杆菌(Helicobacter pylori,HP)感染是慢性胃炎和消化性溃疡的主要病因,与胃癌的发生亦有密切关系,WHO已将HP列为一种致癌因子,但其确切致病机制尚不清楚。从细胞动力学和分子生物学角度探讨HP感染与胃癌的关系是近年来HP研究的热点之一。较长期以来,细胞异常增殖一直被认为是肿瘤生成的重要环节,但现认为细胞增殖与分化异常并非肿瘤发生的唯一因素,细胞凋亡(apoptosis)
作者 吕宾
机构地区 浙江省中医院
出处 《浙江医学》 CAS 1998年第12期763-765,共3页 Zhejiang Medical Journal
  • 相关文献

参考文献8

  • 1Florencia GQ, Gregory JG. Cell death by apoptosis:basic concepts and disense relevance for the gastroenterologist. Gastroenterology,1996.110:1238.
  • 2Alison MR. Liver cett death:patterns and mechanisms. Gut,1994:35:577.
  • 3Reed JC. Bel-2 and the regulation of programmed cell death. J cell Biol, 1994,124:1.
  • 4Mountz JD, Zhou T, Wu J, et al. Regulation of apoptosis in immune cells. J Clin Immunol,1995,15(1):l.
  • 5Nagata S Golstein P, The Fas death factor. Science, 1995,267:1449.
  • 6Moss SF, Calam J, Agarwal B, et al. Induction of gastric epithelial apoptosis by Helicobacter pylori Gut, 1996,38:498.
  • 7董全江,刘文忠,郑雄,萧树东,施尧,彭延申.幽门螺杆菌感染对胃上皮细胞凋亡的影响[J].中华内科杂志,1997,36(11):751-753. 被引量:5
  • 8Tsuji S, Kawano S, Takei Y, et al. Ammonia induces gastric cell apoptosis:possible implication to Helicobacter pylori-related gastric mucosal atrophy. Gastroenterology, 1995, 108:A244.

共引文献4

同被引文献16

  • 1Avramis VI,Nandy P,Kwock R,et al.Increased p21/WAF-1 and p53 protein levels following sequential three drug combination regimen of fludarabine,cytarabine and docetaxel induces apoptosis in human leukemia cells[J].Anticancer Res,1998,18:2327-2338.
  • 2Pepper C,Thomas A,Hoy T,et al.Flavopiridol circumvents Bcl-2 family mediated inhibition of apoptosis and drug resistance in B-cell chronic lymphocytic leukaemia[J].British Journal of Haematology,2001,114:70-77.
  • 3Bellosillo B,Villamor N,López-Guillermo A,et al.Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia[J].Blood,2002,100:1810-1816.
  • 4Gottardi D,De Leo AM,Alfarano A,et al.Fludarabine ability to down-regulate Bcl-2 gene product in CD5+ leukaemic B cells:in vitro/in vivo correlations[J].Br J Haematol,1997,99:147-157.
  • 5Biswal Shyam S,Datta Kaushik,Acquaah-Mensah George K,et al.Changes in ceramide and sphingomyelin following fludarabine treatment of human chronic B-cell leukemia cells[J].Toxicology,2000,154:45-53.
  • 6Nowak D,Boehrer S,Brieger A,et al.Upon drug-induced apoptosis in lymphoma cells X-linked inhibitor of apoptosis (XIAP) translocates from the cytosol to the nucleus[J].Leuk Lymphoma,2004,45:1429-1436.
  • 7Jackson GH.Use of fludarabine in the treatment of acute myeloid leukemia[J].Hematol J,2004,5(Suppl 1):62-67.
  • 8Rao R,Shammo JM,Enschede SH,et al.The combination of flu darabine,cyclophosphamide,and granulocyte-macrophage colony-stimulating factor in the treatment of patients with relapsed chronic lymphocytic leukemia and low-grade Non-Hodgkin's lymphoma[J].Clin Lymphoma,2005,6:26-30.
  • 9Tamburini J,Levy V,Chaleteix C,et al.Fludarabine plus cy clophosphamide in Waldenstrom's macroglobulinemia:results in 49 patients[J].Leukemia,2005,19:1831-1834.
  • 10Li L,Keating MJ,Plunkett W,et al.Fludarabine-Mediated Repair Inhibition of Cisplatin-Induced DNA Lesions in Human Chronic Myelogenous Leukemia-Blast Crisis K562 Cells:Induction of Synergistic Cytotoxicity Independent of Reversal of Apoptosis Resistance[J].Mol.Pharmacol,1997,52:798.

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部