期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

微波催化3-羟基吡啶-4-酮类化合物的合成 被引量：1

Synthesis of 3-hydroxy-4-pyridinones under microwave radiation
下载PDF
导出
摘要 介绍一种微波合成反应装置及其在3-羟基吡啶-4-酮类化合物合成中的应用。应用微波加热回流，使反应时间大大缩短，产率也有所提高。 A microwave-radiation organic synthesis device is introduced. The iron chelators N-substiuted-2-alkyl-3-hydroxy-4 (1H)-pyridinones were prepared by using this device. The reaction time was shortened largely and the yield was raised.
作者 陈卫民 徐继红 曾陇梅
机构地区 第一军医大学药物研究所 中山大学化学与化学工程学院
出处 《第一军医大学学报》 CSCD 1998年第4期282-283,共2页 Journal of First Military Medical University
基金 广东省自然科学基金!940321
关键词 羟基吡啶酮 铁螯合剂 微波催化 微波炉 家用 3-hydroxy-4-pyridinone iron chelator microwave catalysis
分类号 TQ251.1 [化学工程—有机化工]
  • 相关文献

参考文献2

二级参考文献2

共引文献73

同被引文献14

  • 1GRAZINA R, GANO L, SEBESTIK J, et al. New tripodal hydrox- ypyridinone based chelating agents for Fe (Ⅲ), A1 (Ⅲ) and Ga (Ⅲ) : synthesis, physico-chemical properties and bioevaluation [J]. Journal oflnorganic Biochemistry, 2009, 103(2): 262-273.
  • 2CHAVES S, MENDONCA A C, MARQUES M S, et al. A gallium complex with a new tripodal tris-hydroxypyridinonc for potential nuclear diagnostic imaging: solution andin vivo studies of 67^Ga-labeled species [J]. Journal oflnorganic Biochemistry, 2011, 105(1): 31-38.
  • 3LEYDIER A, LECERCLE D, PELLET-ROSTAING S, et al. Seques- tering agent for uranyl chelation: new binaphtyl ligands[ J]. Tetrahedron Letters, 2011, 52(31) : 3973 - 3977.
  • 4STREAM M, TAYLOR P D, HIDER R C, et al. Novel 3-hydroxy-2 ( 1H )-pyridinones. Synthesis, iron ( III )-chelating properties, and bio- logical activity [ J ]. Journal of Medicinal Chenistry, 1990, 33 ( 6 ) : 1749- 1755.
  • 5CLEVETTE D J, NELSON, W O, NORDIN A, et al. Complexation ofaluminum with n-substituted 3-hydroxy-4-pyridinones [ J ]. lnorgartic Chemistry, 1989, 28(11) : 2079- 2081.
  • 6SANq'os M A, GRAZINA R, NETO A Q, et al. Synthesis, chelating properties towards gallium and biological evaluation of two N-substituted 3-hydroxy-4-pyridinones[ J]. Journal of Inorganic Biochemistry, 2000, 78(4) : 303 - 311.
  • 7SANTOS M A, GIL M, GANO L, et al. Bifunctional 3-hydroxy-4- pyridinone derivatives as potential pharmaceuticals: synthesis, complex- ationwith Fe(Ⅲ), Al(Ⅲ) and Ga(Ⅲ) and in vivo evaluation with 67Ga [J]. Journal of Biological Inorganic Cluvnistry , 2005, 10(5): 564- 580.
  • 8SANTOS M A, GRAZINA R, BUGLVO P, et al. A new bipodal car- boxy-bis (hydroxyppidinonate) ligand: synthesis and eomplexation with copper (Ⅱ), nicker (Ⅱ) and zinc (Ⅱ) in aqueous .solution [J]. Poly- hedron, 2002, 21(25): 2609-2616.
  • 9SWAGATIKA D, UASHANKAR D, ARMANDO V R, et al. Bis[3, 5-bis (benzylidene)-4-oxo-l-piperidinyl] amides: a novel class of po- tent eytotoxins[J]. ChemMedChem, 2011, 6(10): 1892-1899.
  • 10JIN C W, DE X W, ZHI T H, et al. Synthesis of diverse N,O- bridged calix [ 1 ] arene [ 4 ] pyridine-C60 dyads and triads and formation of intramolecular self-inclusion complexes [ J ]. Journal of Organic Chemistry, 2010, 75(24): 8604-8614.

引证文献1

二级引证文献4

第一军医大学学报
1998年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部