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分子靶向药物心脏毒副作用的研究 被引量:4

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摘要 肿瘤分子靶向治疗是利用肿瘤组织或细胞所具有的特异性(或相对特异)的结构分子作为靶点,使用某些能与这些靶分子特异结合的抗体、配体等达到直接治疗或导向治疗目的的生物治疗模式。分子靶向治疗有较好的选择性,能减少对正常组织的损伤。但是人体的正常组织与肿瘤组织之间没有绝对界线,当靶向药物通过信号转导通路直接作用于肿瘤组织的时候,正常组织如心脏也会受到损伤。现就分子靶向药物对心脏的毒副作用做简要陈述。
作者 闫敏 潘跃银
出处 《癌症进展》 2010年第1期53-59,共7页 Oncology Progress
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