高压氧治疗新生儿缺氧缺血性脑病的疗效观察

Clinical observation of hyperbaric therapy hypoxicischemic encephalopathy

目的:观察早期高压氧治疗新生儿缺氧缺血性脑病的临床疗效。方法:将50例缺氧缺血性脑病新生儿随机分为治疗组25例和对照组25例,对照组只给予综合治疗,治疗组在综合治疗的基础上加用高压氧治疗,然后观察临床症状的变化情况。结果:治疗组显效48.0%(12/25),有效40.0%(10/25),无效12.0%(3/25),总有效率88.0%;对照组25例,显效24.0%(6/25),有效44.0%(11/25),无效32.0%(8/25),总有效率68.0%。治疗组总有效率显著高于对照组,差异具有显著性(P<0.05)。结论:早期高压氧对治疗新生儿缺氧缺血性脑病有显著疗效。

Objective： To observe the effect of hyperbaric oxygen therapy on neonatal hypoxicischemic encephalopathy（HIE）.Methods： 50 cases of HIE were randomly divided into treatment group and control group,the control group just give comprehensive treatment,the treatment group in comprehensive therapy combined with hyperbaric oxygen therapy,then observe the changes of clinical symptoms.Results： The treatment group total efficient rate（88.0%） was higher than that in control group（68.0%）（P〈0.05）.Conclusion： Hyperbaric oxygen therapy on neonatal hypoxicischemic encephalopathy have remarkable curative effect.