关注抗血管内皮生长因子药物治疗眼部新生血管疾病的潜在风险

Pay attention to the potential risks of anti- vascular endothelial growth factor therapy for neovascular disease

抗血管内皮生长因子（VEGF）药物为眼部新生血管疾病的治疗开辟了新的途径，其有效性和安全性也已经为大量研究工作所证实。但在临床实践中，长期、大剂量的应用抗VEGF药物同时也会带来一些新的问题和并发症．甚至会影响正常眼组织血管生成过程和视网膜的血液供应。因此，必须重视过度抗VEGF治疗眼部新生血管疾病带来的问题和潜在风险。

Anti-vascular dndothelial growth factor （VEGF） drugs have open up a new treatment channel for ocular neovaseular diseases. A lots of clinical data has proved that anti-VEGF drugs are effective and safe. But we should also notice that long term and excessive usage of anti VEGF drugs brings some new problems and complications, and even affect the normal ocular physiological process of the angiogenesis and retinal blood flow. So, it is necessary to pay attention to the problems and potential risks of excessive usage of anti-VEGF therapies for ocular neovascular disease.