腔隙性脑梗死患者图片再认的事件相关电位

A study on event-related potentials of recognition of pictures in patients with lacunar infarct

目的:探讨腔隙性脑梗死(LI)患者记忆功能受损的特点及其事件相关电位的特征。方法:LI组患者30例,同时选取30例健康老年人作为对照组。所有被试者均进行图片再认测验,同时记录脑电图,离线处理后对两组被试者所诱发的ERPs进行分析比较。结果:LI组图片再认的反应时间为746.79±62.07ms,对照组为642.47±53.91ms,两组对比有显著性差异(P<0.01)。LI组图片再认的正确率为70.53%±15.32%,对照组为79.29%±11.01%,两组对比有显著性差异(P<0.05)。LI组所诱发的额区N300波幅低于对照组(P<0.05),潜伏期较对照组延长(P<0.001)。结论:LI患者存在记忆受损,再认能力下降。ERP可作为早期评价LI患者记忆功能的辅助工具。

Objective：To explore the memory impairment in patient with lacunar infarct（LI） and the related changes in eventrelated potentials（ERPs）.Method：Thirty subjects with LI were selected and matched by 30 normal controls.All subjects received an image recognition task and the EEG signals were recorded simultaneously.ERPs of each group off-line were analyzed and compared.Result：In image recognition tasks,reaction time（RT） were （746.79±62.07）ms in LI group and （642.47±53.91）ms in control group.and RT in LI group was longer than that in control group （P 〈0.01）.The accuracy rats were 70.53%±15.32% in LI group and 79.29%±11.01% in control group,and accuracy rate in control group was higher than that in LI group（P〈0.05）.There were significant differences in both latency（P〈0.001） and amplitude（P〈0.05） of N300 between the two groups.Conclusion：Patients with LI have memory impairment for recognition.ERP can be used for the early evaluation of memory function in patients with LI.