摘要
溶血磷脂酸是一种细胞间磷脂类信号分子,通过G蛋白偶联受体参与多种肿瘤的发生和发展,本文就溶血磷脂酸的结构及生物学作用在消化系肿瘤发生、发展中的作用机制进行探讨.
Lysophosphatidic acid is an important intercellular lipid mediator that acts through G-protein coupled receptors to mediate the development and progression of a variety of tumors.In this article, we will summarize the structure and physiological function of lysophosphatidic acid and review its role in the pathogenesis of colon cancer, gastric cancer, liver cancer and other gastrointestinal tumors.
出处
《世界华人消化杂志》
CAS
北大核心
2010年第3期276-279,共4页
World Chinese Journal of Digestology
基金
国家自然科学基金资助项目
No.30760275
广西科学基金资助项目
No.0832008~~
关键词
溶血磷脂酸
消化系肿瘤
G蛋白偶联受体
Lysophosphatidic acid
Gastrointestinal tumor
G protein-coupled receptor
