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2005～2008年抗HIV-1化学治疗新药的重要研究进展 被引量：2

Advances in novel anti-HIV-1 drugs and drug candidates:2005-2008
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摘要 人类免疫缺陷病毒(human immunodeficiency virus,HIV)和获得性免疫缺陷综合征(acquired immunodeficiency syndrome,AIDS)仍然是全球关注的健康问题,研究开发新型抗HIV化学药物具有重要意义,上市新药的成功研发案例对此可能有借鉴之处。本文对2005～2008年间FDA批准上市的抗HIV-1化学药物及部分候选药物的发现过程和生物活性特点进行了综述。 HIV and AIDS remain as the crucial global health concern,therefore,research and development of novel anti-HIV-1 chemical therapeutics is still of paramount significance,which may be illuminated by cases of successful marketed drugs.Herein,we document the discovery and biological profile of new anti-HIV-1 drugs approved by FDA between 2005 and 2008 and some drug candidates are also discussed.
作者 郑朴荣 薛海 肖志艳 刘刚
机构地区 中国医学科学院、北京协和医学院药物研究所
出处 《药学学报》 CAS CSCD 北大核心 2010年第2期154-164,共11页 Acta Pharmaceutica Sinica
关键词 艾滋病 HIV-1 药物发现 研究进展 AIDS HIV-1 drug discovery review
分类号 R916 [医药卫生—药学]
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共引文献15

同被引文献34

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药学学报
2010年 第2期

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