伴攻击行为精神分裂症患者临床特征的对照研究

Clinical features of schizophrenia with attack behavior

目的对比分析伴攻击行为精神分裂症患者的临床特点,为临床防范攻击行为积累资料。方法对122例伴攻击行为的精神分裂症患者(研究组)进行一般资料、量表资料调查,并与同期住院且一般资料相匹配的122例不伴攻击行为者(对照组)对照。结果攻击行为的发生率为24.4%;攻击行为者中71.3%发生于住院的第1周内;研究组多数病前性格不良,而且既往多有攻击行为史,两组差异有统计学意义(P<0.05-0.01);研究组的简明精神病量表(BPRS)总分、思维障碍、激活性和敌对猜疑因子分和阳性症状量表(SAPS)总分均显著高于对照组(P<0.05-0.01)。结论精神分裂症伴攻击行为者具有其临床特点,必须加强治疗和监护,以防范其攻击行为的发生。

Objective To compare and analyze the clinical features of schizophrenia with attack behavior, so as to accumulate data to guard against it. Methods 122 cases of schizophrenia with attack behavior （ study group） were investigated on general data and scales assessments. Then,they were compared with 122 those without attack behavior （ control group） with the same general data. Results The incidence of attack behavior was 24.4% in schizophrenia. 71.3% of patients with attack behavior happened during the first week of hospitalization. In the study group, more patients had past history of attack behavior and bad temperament before fall - ill （ P 〈 0.05 or 0. 01 ）. The total score of Brief Psychiatric Rating Scale （BPRS） and thought disorder factor, activity factor, hostility factor and SAPS total score showed significantly higher than those of the control group （ P 〈 0.05 or 0.01 ）. Conclusion Attack behaviors in patients with schizophrenia had their clinical features. The importance must be paid on the treatment and supervision of schizophrenia with attack behaviors, so as to guard against attack behaviors.