伴有抑郁症状孕妇睡眠质量分析

Analysis of sleep quality in pregnant women with depression

目的了解伴有抑郁症状孕妇的睡眠质量并分析其特点。方法对2007年6月至2008年6月在大坪医院(所)妇产科门诊进行产检就诊、伴有抑郁症状的孕妇(研究组,n=45)和健康孕妇(对照组,n=45)进行匹兹堡睡眠质量指数量表(Pittsburgh sleep quality index,PSQI)评定及多导睡眠图(polysomonography,PSG)监测。结果伴有抑郁症状的孕妇PSQI总分(11.46±4.78)分,睡眠质量差的占93.3%,对照组PSQI总分(6.35±3.28)分,睡眠质量差的占26.7%,研究组入睡时间、睡眠时间、睡眠效率、睡眠障碍、日间功能障碍因子分及PSQI总分均明显高于对照组(P<0.05)。与对照组比较,研究组总睡眠时间减少,睡眠潜伏期长(P<0.01),觉醒次数及时间增多,睡眠效率明显下降(P<0.05);浅睡(S1期睡眠)增加而深睡(S3、S4期睡眠)减少,S1期睡眠与S3+S4期睡眠组间比较差异有统计学意义(P<0.01,P<0.05)。与对照组比较,研究组快速眼动睡眠(rapid eye movement,REM)潜伏期缩短,REM睡眠时间增多(P<0.05)。结论伴有抑郁症状的孕妇主、客观睡眠质量均差,以入睡困难、易醒、REM潜伏期缩短及REM睡眠时间增多为其特点。

Objective To understand and analyse its characteristics of the sleep quality in pregnant women with depression. Methods Forty-five pregnant women with depression and 45 matched healthy pregnant women who had pregnancy check-ups in the Department of Gynecology and Obstetrics of our Hospital from June 2007 to June 2008 were enrolled in this study. All of them were informed of the purpose of this study and signed an informed consent form. The protocol and consent form were approved by the Ethics Committee of our university. The Pittsburgh Sleep Quality Index （PSQI） and polysomonography （PSG） were performed in all subjects. Results In pregnant women with depression, the total PSQI score was 11.46±4.78, and 93.3% of them had poor sleep quality. In the health control group, the total PSQI score was 6.35 ±3.28, and 26.7% had poor sleep quality. The depression group had higher score in sleep latency, sleep duration, sleep efficiency, sleep disturbance, day dysfunction and PSQI total score （ P 〈 0.05 ）. By comparing with control group, the depression group had shorter total sleep duration （ P 〈 0.05 ） , longer in sleep latency （ P 〈 0.01 ） , more waking frequency, and lower sleep efficiency （ P 〈 0.05 ） , increased light sleep （ S1 ）, but decreased deep sleep（ S3 and S4）. There was significant differences in the sleep periods of S1 and S3 ＋ S4 between 2 groups （ P 〈 0.05, 0.01 ）. The depression group had shorter rapid eye movement （REM） sleep latency and prolonged REM time （P 〈 0. 05 ）. Conclusion Pregnant women with depression have poor sleep quality in both subjective and objective views, with the charateristics of difficult falling asleep, festless sleep, shorter REM sleep latency and longer REM time.