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三阴乳腺癌研究进展

Progression of triple-negative breast cancer
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摘要 三阴乳腺癌(TNBC)具有独特的生物学行为和临床特征,目前尚没有针对TNBC的标准治疗。近年来在TNBC的流行病学、分子特征、化学治疗和靶向治疗等方面进行了许多研究与探索,特别是Ⅱ期或Ⅲ期临床研究初步结果显示,新的化疗方案和靶向治疗对TNBC可能具有很好的疗效。 Triple-negative breast cancer(TNBC) has distinct biological and clinical characteristics. Therapeutic strategies for TNBC remain a challenge. Studies about epidemiology, molecular characteristics, chemotherapy and targeted-therapy are ongoing, In particular, preliminary results of stage Ⅱ or Ⅲ clinical trials indicate new chemotherapy or combination targeted therapy may have a good efficacy.
出处 《国际肿瘤学杂志》 CAS 2009年第12期922-925,共4页 Journal of International Oncology
关键词 乳腺肿瘤 三阴 治疗 预后 Breast neoplasms Triple negative Therapy Prognosis
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  • 1Nielsen TO. Hsu FD, Jensen K, et al. Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res, 2004, 10(16) :5367-5374.
  • 2Rakha EA, Ellis IO, Reis-Filho JS. lmmunohistochemical heterogeneity of breast carcinomas negative for estrogen receptors, progesterone receptors and Her2/oeu (basal-llke breast carcinomas ). Mod Pathol, 2008, 21 ( 8 ) : 1060-1061.
  • 3Rakha EA, El-Sayed ME, Green AR, et al. Prognostic markers in tripLe-negative breast cancer. Cancer, 2007, 109(1) :25-32.
  • 4Rouzier R, Perou CM, Symmans WF, et al. Breast cancer molecular subtypes respond differently to preoperative chemotherapy. Clin Cancer Res, 2005, 11(16) :5678-5685.
  • 5Rana FN. A retrospective review of demographics and stage of triplenegative breast cancer. ASCO Meeting Abstracts, 2009, 27: e11553.
  • 6Morris GJ, Naidu S, Topham AK, et al. Differences in breast carcinoma characteristics in newly diagnosed African-American and Caucasian patients: a single-institution compilation compared with the National Cancer Institute' s Surveillance, Epidemiology, and End Resuits database. Cancer, 2007, 110(4) :876-884.
  • 7Carey LA. Perou CM, Livasy CA, et al. Race, breast cancer sub-types, and survival in the Carolina Breast Cancer Study. JAMA, 2006, 295 (21) :2492-2502.
  • 8Kurebayashi J, Moriya T, Ishida T, et al. The prevalence of intrinsic subtypes and prognosis in bteast cancer patients of different races. Breast, 2007, 16 ( Suppl 2 ) : S72-S77.
  • 9Kim MJ, Ro JY, Ahn SH, et al. Clinicopathologic significance of the basal-like subtype of breast cancer: a comparison with hormone receptor and Her2/neu-overexpressing phenotypes. Hum Pathol, 2006, 37(9) : 1217-1226.
  • 10Yin W J, Lu JS, Di GH, et al. Clinicopathological features of the triple-negative tumors in Chinese breast cancer patients. Breast Cancer Res Treat, 2009, 115(2) :325-333.

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