有糖尿病家族史13～15岁青少年肥胖特点分析

Characteristics of obesity in teenage with a family history of type 2 diabetes

根据父母有无糖尿病将1619名13～15岁青少年分为糖尿病家族史阳性（FHD^＋）组和糖尿病家族史阴性（FHD^-）组。FHD^＋组的腰围（WC）、腰臀比（WHR）和腰围身高比（WhtR），均高于FHD^-组（P〈0．01）。以WC定义的腹型肥胖检出率FHD^＋组高于FHD^-组（P〈0．01），以体重指数（BMI）定义的超重肥胖检出率差异无统计学意义。应用logistic回归分析，校正性别和年龄，FHD^＋组单纯WC升高及BMI和WC均高者分别是FHD组的2．029（1．211—3．400）和1．364（1．043—1．784）倍（P〈0．05）。2型糖尿病患者的一级亲属13～15岁青少年已存在以腹型肥胖为特点的肥胖趋势。

A cross-sectional study was conducted on 1619 youngsters aged 13 - 15. They were divided into two groups ： one with family history of diabetes （ FHD^＋ ） and another without a family history of diabetes （FHD^-）. Measurements included height, weight, waist circumference （WC） and hip. FHD ^＋ group had significantly higher WC measurement, waist-to-hip ratio （WHR） and waist-to-height ratio （WHtR） when compared with FHD- group （P 〈 0.01 ）. The abdominal obesity rate defined by WC measurement in FHD^＋ group was higher than that in FHD - group （ P 〈 0. 01 ）. The rate of overweight and obesity defined by body mass index （BMI） were no significant difference between two groups. After adjusting the gender and age, logistic regression analysis showed that the odds ratios of WC alone and BMI ＋ WC for FHD ^＋ were 2. 029 and 1. 364 （95% CI： 1. 211 - 3. 400, 1. 043 - 1. 784, P 〈 0. 05 ） respectively. Our data suggest that teenage with a family history of type 2 diabetes has a tendency of overweight characterized by the abdominal obesity.