生物大分子纳米孔分析技术研究进展

Progress of Research on Nanopore-macromolecule Detection

脱氧核糖核酸穿越纳米孔动力学研究以及利用纳米孔开展新型DNA测序技术研究是后人类基因组计划的热点之一。本文对生物纳米孔、固态纳米孔以及纳米孔生物大分子识别技术的研究现状进行了归纳和总结,并对该领域的发展趋势进行展望。

After Human Gene Project,studying the kinetics of DNA translocation through a nanopore,and developing a novel fast DNA sequencing technology by using nanopore have become one of the hot in gene-research.This contribution provides an overview of nanopore macromolecular identification,including bionanopore and solid-state nanopore,while the perspective of these research are also summarized.