血管性突发性耳聋神经介入治疗的临床探讨

Research on sudden deafness by vascular interventional therapy for neurology

目的探讨神经血管介入技术对血管性突发性耳聋的疗效。方法将46例血管性突发性耳聋患者随机分为2组,动脉组22例,行脑血管造影,将微导管超选择置于小脑前下动脉,给予尿激酶30万~50万U于20~30 min注完;静脉组采用常规静脉给予扩血管、降纤药物治疗,对2组的疗效进行比较,疗效标准采用1997年中华医学会耳鼻喉科学会颁布的疗效分级。结果动脉组痊愈10例,显效6例,有效4例,无效2例;静脉组痊愈4例,显效3例,有效9例,无效8例。结论超选择局部动脉内给药可能是治疗血管性突发性耳聋的有效方法。

Objective To explore the effect interventional neurovascular techniques in the treatment of sudden deafness.Methods All 46 cases of sudden deafness of vascular disease were randomly divided into two groups,22 cases of artery group were given the cerebral angiography,superselective micro-catheter placed anterior inferior cerebellar artery,30 cases give were urokinase 500,000 U in 20~30 minutes after injection.Conventional group were given conventional intravenous vasodilative,defibrase medication,the efficacy of the two groups were compared by the criterion used by the Chinese Medical Association in 1997 issued by the Institute of Otorhinolaryngology classification efficacy.Results Artery group healed in 10 cases,markedly effective in 6 cases,effective in 4 cases and ineffective in 2 cases;In intravenous group,four cases recovered,3 cases of markedly effective in 9 cases,8 cases of null and void.Conclusion Superselective local intra-arterial administration may be an effective way sudden deafness of vascular.