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利培酮合并舍曲林治疗慢性精神分裂症的对照研究 被引量:6

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摘要 目的评价利培酮合并舍曲林治疗慢性精神分裂症阴性症状和副作用。方法将64例慢性精神分裂症患者随机分为单用组(利培酮组)与合用组(利培酮十舍曲林组),采用阳性症状和阴性症状量表(PANSS)、阴性症状量表(SANS)和副反应量表(TESS)分别于治疗前、治疗后4、8、12周进行疗效及副反应评定。结果治疗8周后合用组PANSS总分、阴性因子分、SANS总分及分量表分均比治疗前明显下降,且阴性因子分显著低于单用组。治疗后4、8、12周TESS评分,合用组低于单用组。结论利培酮合并舍曲林能明显改善慢性分裂症,且副作用较少。
作者 潘勇 庞波
机构地区 安徽省荣军医院
出处 《精神医学杂志》 2010年第1期42-43,共2页 Journal of Psychiatry
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二级参考文献9

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同被引文献70

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