咳嗽变异性哮喘的临床分析

The Clinical Analysis of Cough Variant Asthma

目的探讨咳嗽变异性哮喘的诊断和治疗。方法回顾性分析咳嗽变异性哮喘的临床特点、诊断要点和治疗效果。结果36例咳嗽变异性哮喘患者,肺功能支气管舒张试验FEV1变异率>15%,支气管舒张试验阳性,明确诊断为咳嗽变异性哮喘。给予沙美特罗/替卡松(50/100μg)和孟鲁斯特,随访观察2月后,测定ACT及用药后肺功能舒张试验FEV1上升程度,测定疗效结果,其中30例FEV1变异率<15%,咳嗽症状明显改善,改善率为83.3%。结论对有慢性咳嗽患者,在排除其它原因咳嗽外,要常规进行支气管舒张试验,明确诊断后使用小剂量沙美特罗/氟替卡松和孟鲁斯特,治疗咳嗽变异性哮喘效果良好。

Objective To investigate the diagnosis and therapy of patients with cough variant asthma. Methods Retrospective analysis of cough variant asthma was carried out. The clinical characteristic, main points of diagnosis and therapeutic efficacy were evaluated in the study. Results Among 36 cases for chronic cough,pulmonary function bronchodilation test FEV1 Variation Rate 〉 15%, bronchodilation test was positive, to be diagnosed as Cough-Variant-Asthma patients, treated by Salmeterol/Fluticaso （50/ 100μg） and Montelukast. After 2 months of follow up observation;the ACT was determined and pulmonary function bronchodilation test FEV1 was performed. Among the 30 patients, the FEV1 Variation Rate 〈 15%, cough symptom improved obviously, improving rate was 83.3%. Conclusion For chronic cough patients,besides ruling out other cough reasons, the bronchodilation test should be taken; after diagnosis, the effactive was fine when treated for Cough-Variant-Asthma by small dose of Salmeterol/Fluticaso and Montelukast.