血及尿钠钾对肝硬化腹水患者利尿效果的评估

Evaluation on Diuretic Efficiency by Detecting Serum and Urinary Electrolyte Concentrations in Cirrhotic Patients with Ascites

目的通过同步检测43例肝硬化腹水患者的血钠、血钾、24小时尿钠、24小时尿钾及尿钠/尿钾的比值对肝硬化腹水患者的利尿效果进行评估。方法肝硬化腹水患者43例,在利尿剂使用前后,同步检测肝、肾功能、血钠、血钾、24小时尿钠、24小时尿钾,并记录24小时尿量,测体重、腹围。结果利尿剂使用前后,患者的24小时尿钠、24小时尿钾、24小时尿量、体重、腹围有明显差异,提示24小时尿钠、24小时尿钾、24小时尿量的测定可以早期反映利尿剂的利尿效果。结论同步检测肝硬化腹水患者的血、尿电解质,可以早期判断是否为难治性腹水,为决定治疗方案及早期判断预后提供临床依据。

Objective To explore the evaluation of diuretic efficiency by synchronous detecting serum sodium and potassium,24 hours urinary sodium and potassium, and the ratio of urinary sodium to urinary potassium in cirrhotic patients with ascites. Methods 43 cirrhotic patients with ascites were enrolled in the study. The liver function, renal function, serum sodium and potassium, 24 hours urinary sodium and potassium, urine volume of 24 hours, body weight and abdominal circumference were detected before and after the administration of diuretic. Results After the administration of diuretic,24 hours urinary sodium and potassium, u- rine volume of 24 hours,body weight and abdominal circumference had significantly changed. Conclusion The synchronous detections of serum and urinary electrolyte concentrations is helpful to the diagnosis of refractory ascites, and provide the clinical basis for the treatment and early prognosis judgment.