肿瘤坏死因子-α与结核病关系的研究进展
被引量:6
Research progress on relationship between tumour necrosis factor-ɑ and tuberculosis.
摘要
肿瘤坏死因子-ɑ(Tumour necrosis factor-alpha,TNF-ɑ)是一种具有广泛生物学效应的多功能细胞因子,它与结核的发生、病程、转归、复燃及治疗都有密切的关系。近年来TNF-ɑ在结核发病中的免疫机制日益受到重视,现对TNF-ɑ在控制结核感染中的枢纽作用,尤其是TNF-ɑ对结核肉芽肿形成的影响,并探讨TNF-ɑ拮抗剂应用于炎性疾病治疗时所存在的结核病风险做一综述。
出处
《中国热带医学》
CAS
2010年第3期370-372,共3页
China Tropical Medicine
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