摘要
①目的：检测结直肠癌中CD105的表达，探讨其在结直肠癌发生、发展及转移中的作用及相互关系。②方法：应用流式细胞术检测80例结直肠癌标本中CD105的表达。③结果：CD105在结直肠癌组织中的表达量明显高于正常大肠粘膜，不同Dukes分期之间、不同分化程度结直肠癌组织之间CD105表达差异有统计学意义（P〈0．05）。④结论：结直肠癌中有血管形成，CD105可能是判断病人预后的指标。
Objective： To detect the expression of CDI05 and discuss their correlation of the pathogenesis, development and metastasis in colorectal adenocarcinoma. Methods： The expression of CD105 protein in colorectal adenocarcinoma tissues obtained from 80 patients who underwent radical resection was detected by FCM. Results： Comparisons between the primary tumors with colorectal adenocarcinoma and normal tissues showed that there was a significant expression of CD105. Moreover, the expression of CD105 was associated with Dukes stages, differentiation （P〈0.05）.Conclusions： There was angiogenesis in the colorectal adenocarcinoma .The expression of CD105 may be a significant prognostic indicator.
