严重烧伤患者早期血清脂联素水平分析

The Diversify of APN in the Patient of Sever Burn at the Early Stage of Burn Injury

目的探讨严重烧伤早期应激性高血糖患者血清脂联素的表达水平及临床意义。方法选取2007--2009年烧伤患者64例其中严重烧伤患者36例，伤后5～12h出现高血糖者25例（A组），血糖正常者11例（B组），28例中度烧伤血糖正常患者作为对照组（C组）。分别动态检测烧伤后3、5、12、24、120h患者血糖、血清脂联素（APN）、尿素氮（BUN）、肌酐（Cr）含量的变化。结果严重烧伤患者应激性高血糖（A组）一般出现在伤后3～24h；A组的血清脂联素水平低于B组和C组。结论严重烧伤患者血清脂联素水平与烧伤的严重程度有关，与应激性高血糖的关系需进一步探讨。

Objective To explore the level and clinical significance of APN in the patients of the stress hyperglycemia at the early stage of burn injury. Methods The total number of 64 burn injury patients from 2007 to 2009 were divided into 3 groups, 25 cases are sever burn accompany the stress hyperglycemia after 5 - 12 hours（ A group）. 11 cases were sever burned（ B group） , 28 cases were considered control group （C group） , with moderate degree burn , but wth euglycemia. We detected the variance of BG, serum APN, BUN,CR in the burn injury patients after 3h,Sh, 12h,24h,120h. Results The date between 5 - 12h, the stress hyperglycemia at the early stage of burn injury, the level of APN in A and B groups is higher than in C group. Conclusion At the early stage of severe bum, The variety of serum APN have a relation with degree of burn, we need more explore the relation with the stress hyperglycemia at the early stage of burn injury.