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正常人群中流感嗜血杆菌的分布及其药敏分析的研究

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摘要 目的:分析嗜血杆菌在本地区正常人群中的分布及其药敏情况,为临床治疗提供参考依据。方法:对在本院参加体检的正常人群进行咽拭子和鼻拭子培养,用V因子、X因子试验及API鉴定条鉴定嗜血杆菌,用头孢硝噻吩滤纸片法测定β-内酰胺酶检测,纸片琼脂扩散(K-B)法测定嗜血杆菌对8种抗生素的耐药率。结果:820例鼻、咽拭子标本,共分离出98例流感嗜血杆菌,检出率为11.95%。流感嗜血杆菌对青霉素敏感率仅为15.31%,对氨苄西林、头孢噻肟、头孢呋辛、阿奇霉素的敏感率分别为65.31%、83.67%、83.67%、98.98%。结论:健康人群中上呼吸道流感嗜血杆菌的携带率也较高,对青霉素、环丙沙星等药物的耐药率较高,阿奇霉素等是治疗嗜血杆菌的有效抗生素,应重视流感嗜血杆菌的培养分离及耐药性的检测,应加强对嗜血杆菌的培养及耐药性检测。
出处 《中国当代医药》 2010年第5期131-132,共2页 China Modern Medicine
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