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Forkhead-box A1转录因子与乳腺癌

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摘要 Forkhead—box A1(FOXA1)基因亦为hepatocyte nuclear factor 3α基因(HNF3α),是转录因子FOX家族中的一员,在人体许多组织如乳腺、肺、食管、肝、胰腺、膀胱和前列腺等部位中可见其表达,能与百余个基因的启动子相结合,共同调整细胞信号和细胞周期,且在许多肿瘤的发生中都有FOXA1的参与。
作者 刘宁 牛昀
出处 《中华病理学杂志》 CAS CSCD 北大核心 2010年第2期136-139,共4页 Chinese Journal of Pathology
基金 国家自然科学基金(30872519) 教育部长江学者和创新团队计划(TRT0743)
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