参照C28-A2确定胱抑素C的参考值范围

Determine the reference intervals of cystatin C according to CLSI C28-A2

目的建立本实验室胱抑素C（胱氨酸蛋白酶抑制剂，Cytatin C，Cys-C）免疫透射比浊法测定试剂盒的参考值范围。方法随机抽取240例健康人员的新鲜血清，利用市售胱抑素C测定试剂盒（免疫透射比浊法）进行测定，测定结果按CLSIC28-A2（临床实验室参考值范围的定义和确认．第2版）进行统计处理。结果本实验室1～49岁健康人群胱抑素C参考值范围为0．59—1．06mg／L，50-88岁健康人群胱抑素C参考值范围为0．48～1．32mg／L。结论实验室有．必要根据CLSIC28-A2文件的规定建立自己的参考值范围。

Objective To build the reference intervals of Cystatin C. Methods Randomly collecting 240 samples of health persons,test them by systatin C assay kit（ Immunohurbidimetry method） and count the resuhs according to CLSI C28-A2 （How to define and determine reference intervals in the clinical laboratory;approved guideline-second edition）. Results Con- firmed the reference intervals of cystatin C is 0. 59 - 1.06mg/L to 1 -49 years old people,and 0. 48 - 1.32mg/L to 50 - 88 years old people. Conclusion It is necessary for labarotory to determine its own reference intervals aecordinge to the C28-A2.