期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

NF-κB的活性对TRAIL诱导肿瘤凋亡的影响研究进展 被引量：2

下载PDF
导出
作者 严青春 熊小亮 俞薇薇 龚自力
机构地区 江西南昌大学医学院病理学教研室
出处 《肿瘤防治研究》 CAS CSCD 北大核心 2010年第2期239-241,共3页 Cancer Research on Prevention and Treatment
基金 江西省教育厅科技计划资助项目(GJJ08089)
关键词 NF-ΚB TRAIL 肿瘤 凋亡
分类号 R979.1 [医药卫生—药品]
  • 相关文献

参考文献23

  • 1Sen R, Baltimore D. Multiple nuclear factors interact with the immunoglobulin enhancer sequences[J ]. Cell, 1986 , 46 (5) : 705-716.
  • 2Zhang L, Fang B. Mechanisms of resistance to TRAIL-induced apoptosis in cancer [J]. Cancer Gene Ther, 2005,12 (3): 228-237.
  • 3Wachter T, Sprick M, Jausmann D, et al. cFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF kappaB activation at the death-inducing signaling complex in human keratinocytes [J]. J Biol Chem,2004 ,279(51 ):52824-52834.
  • 4Kim KM, Lee YJ. Amiloride augments TRAIL-induced apoptotic death by inhibiting phosphorylation of kinases and phosphatases associated with the P13K-Akt pathway [J]. Oncogene, 2005,24 (3) : 355-366.
  • 5Arenzana Seisdedos F, Turpin P, Rodriguez M, et al. Nuclear localization of I kappa B alpha promotes axtive transport of NF kappa B from the mucleus to the cytoplasm [J]. Oncogene, 1999,18(49):6867-6874.
  • 6Shen J,Channavajhala P, Seldin DC. et al. Phosphorylation by the protein kinase CK2 promotes calpain-mediated degradation of IkappaBalpha[J]. J Immunol,2001,67(9) :4919-4925.
  • 7Chen X, Kandasamy K, Srivastara PK, et al. Differential roles of RelA (p65) and c-Rel subunits of nuclear factor kappa B in tumor necrosis factor related apoptosis-inducing ligand signaling[J]. Cancer Res,2003,63(5):1059-1066.
  • 8Oya M, Ohtsubo M, Takayanagi A, et al. Constitutive activation of nuclear factor kB prevents TRAIL-induced apoptosis in renal cancer cells[J]. Oncogene, 2001,20 (29) : 3888-3896.
  • 9Bernard D, Quatannens B, Vandenbunder B, et al. Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand ( TRAIL )-induced apoptosis by up-regulating the TRAIl. decoy receptor DcR1 [J]. J Biol Chem,2001,276(29) :27322-27328.
  • 10Baetu TM,Kwon H,Sharma S,et al. Disruption of NF-kappaB signaling reveals a novel role for NF-kappaB in the regulation of TNF related apoptosis inducing ligand expression[J]. J Immunol,2001,167(6) :3164-3173.

二级参考文献26

  • 1郝继辉,郝希山,俞鸣,史玉荣,李强.肿瘤坏死因子凋亡诱导配体诱导结肠癌细胞凋亡的机制[J].中华实验外科杂志,2005,22(12):1496-1498. 被引量：5
  • 2王同杉,游思洪,葛红梅,陈子庆,丁小健,刘平.凋亡抑制蛋白livin在人胃癌中的表达以及和survivin表达的关系[J].南京医科大学学报（自然科学版）,2006,26(1):39-43. 被引量：49
  • 3董荣春 周荣华 吕发度 等.SMMC-7721人肝癌细胞株的建立及其生物学特性的初步观察[J].第二军医大学学报,1980,1:5-9.
  • 4Staunton MJ,Gaffney EF.Tumor type is a determinant of susceptibility to apoptosis.Am J Clin Pathol,1995,103:300-307.
  • 5Nozawa F,Itarmi A,Saruc M,et al.The combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo2L) and Genistein is effective in inhibiting pancreatic cancer growth.Pancreas,2004,29:45-52.
  • 6Mizutani Y,Nakanishi H,Yoshida O,et al.Potentiation of the sensitivity of renal cell carcinoma to TRAIL-mediated apoptosis by subtoxic concentration of 5-fluorouracil.Eur J Cancer,2002,38:167-176.
  • 7Wang CY,Mayo MW,Korneluk RG,et al.NF-kappaB antiapoptosis:induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation.Science,1998,281:1580-1683.
  • 8Mitsiades N,Mitsiades CS,Poulaki V,et al.Biologic sequelae of nuclear factor-κB blockade in multiple myeloma:therapeutic applications.Blood,2002,99:4079-4086.
  • 9Ghosh S,May MJ,Kopp EB.NF-kappa B and Rel proteins:evolutionarily conserved mediators of immune responses.Annu Rev Immunol,1998,16:225-260.
  • 10Banerjee D,Liefshitz A.Potential of the proteasomal inhibitor MG-132 as an anticancer agent,alone and in combination.Anticancer Res,2001,21:3941-3947.

共引文献15

同被引文献29

  • 1Wiley SR, Schooley K, Smolak PJ, et al. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity, 1995,3 (6) : 673-682.
  • 2Yoldas B, Ozer C, Ozen O, et al. Clinical significance of TRAIL and TRAIL receptors in patients with head and neck cancer. Head Neck, 2011,33(9) : 1278-1284.
  • 3Shivapurkar N, Toyooka S, Toyooka KO, et al. Aberrant methylation of trail decoy receptor genes is frequent in multiple tumor types. Int J Cancer, 2004,109 (5) : 786-792.
  • 4Trarbach T, Moehler M, Heinemann V, et al. Phase 11 trial of mapatumumab, a fully human agonistie monoelonal antibodythat targets and activates the tumour necrosis factor apoptosis- inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer. Br J Cancer, 2010,102(3) :506-512.
  • 5Jiang M, Liu Z, Xiang Y, et al. Synergistic antitumor effect of AAV-mediated TRAIL expression combined with cisplatin on head and neck squamous cell carcinoma. BMC Cancer, 2011,11:54.
  • 6Lashinger LM, Zhu K, Williams SA, et al. Bortezomib abolishes tumor necrosis factor-related apoptosis-inducing ligand resistance via a p21-dependent mechanism in human bladder and prostate cancer cells. Cancer Res, 2005,65 ( 11 ) : 4902-4908.
  • 7Nikrad M, Johnson T, Puthalalath H, et al. The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim. Mol Cancer Ther, 2005,4(3) :443-449.
  • 8Koschny R, Holland H, Sykora J, et al. Bortezomib sensitizes primary human astrocytoma cells of WHO grades I to IV for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. Clin Cancer Res, 2007,13 ( 11 ) : 3403-3412.
  • 9Shim SH, Lee CT, Hun Hah J, et al. Conditionally replicating adenovirus improves gene replication efficiency and anticancer effect of El-deleted adenovirus carrying TRAIL in head and neck aquamous cell carcinoma. Cancer Sci, 2010,101 (2) :482-487.
  • 10Elord HA, Fan S, Muller S, et al. Analysis of death receptor 5 and caspase-8 expression in primary and metastatic head and neck squamous cell carcinoma and their prognostic impact. PLoS One, 2010,5(8) :e12178.

引证文献2

二级引证文献3

肿瘤防治研究
2010年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部