应用三维超声检测孕11^(+2)～14^(+2)周胎儿颈部透明层厚度的可行性分析

The feasibility of nuchal translucency measurement at 11^(+2) to 14^(+2) weeks of gestation using three-dimensional ultrasound

目的:探讨利用三维超声技术获得标准正中矢状切面测量颈部透明层(NT)厚度的可行性,评价三维超声技术在此方面是否有优越性。方法:对198例孕11+2～14+2周的胎儿应用二维超声及三维超声分别测量胎儿NT厚度,对比二者测量值是否有统计学差异。结果:对198例检测结果进行统计学分析,结果显示三维超声测量NT值与二维超声测量NT值统计学上无显著性差异(t=0.488,P=0.626>0.05),二者之间具有可比性,二者测得的NT值均与孕周呈正相关,三维超声及二维超声测得NT厚度与孕周相关系数分别为r=0.536,P<0.05;r=0.543,P<0.05。结论:应用三维超声重建功能及三维扩展成像技术能够获得测量胎儿NT厚度所需的标准正中矢状切面,因此三维超声在检测胎儿NT厚度方面是可行的。

Objective：To evaluate the feasibility of nuchal translucency（NT） measurement through standard midsagittal section acquired by three-dimensional（3D） ultrasound.Methods：198 cases of 11＋2～14＋2 weeks of gestational age fetus underwent 2D and 3D ultrasound, NT was measured, comparative measurements between 2D and 3D ultrasound were performed to see whether there was significant difference.Results：The statistical assessment for all the 198 fetuses showed that the difference of NT values measured by 2D and 3D ultrasound was not significant（t=0.488, P=0.6260.05）, positive correlations were found between NT value and gestational age for both methods（r=0.536, P0.05;r=0.543, P0.05）.Conclusion：Reconstruction and 3D extended imaging could obtain standard midsagittal section essential for NT measurement, so it is feasible to measure NT by 3D ultrasound, and its clinical value should be confirmed.