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化脓性结核病患者T淋巴细胞亚群分类变化特征 被引量:4

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摘要 目的:检测化脓性结核病患者外周血和病灶处脓液T淋巴细胞亚群分类,探讨化脓性结核病患者免疫状态。方法:对30例结核病组患者外周血标本和病灶处脓液标本各30份应用流式细胞仪在单个核细胞水平检测T淋巴细胞亚群分类;选取20例健康体检者外周血标本20份作对照。结果:结核病组外周血中CD4+淋巴细胞百分含量低于对照组,CD8+淋巴细胞百分含量高于对照组,2组比较差异有统计学意义(P<0.01);结核病组病灶处CD4+淋巴细胞数高于对照组(P<0.01),CD8+淋巴细胞数与对照组比较差异无统计学意义(P>0.05)。结论:化脓性结核病的发生与T淋巴细胞亚群失衡有关,表现为外周血中CD4+细胞数量减少,而局部病灶中CD4+细胞增加。
出处 《中华实用诊断与治疗杂志》 2010年第3期300-301,共2页 Journal of Chinese Practical Diagnosis and Therapy
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